Thursday, September 29, 2016

Labocort




Labocort may be available in the countries listed below.


Ingredient matches for Labocort



Hydrocortisone

Hydrocortisone 21-acetate (a derivative of Hydrocortisone) is reported as an ingredient of Labocort in the following countries:


  • Chile

International Drug Name Search

Losamet




Losamet may be available in the countries listed below.


Ingredient matches for Losamet



Losartan

Losartan potassium salt (a derivative of Losartan) is reported as an ingredient of Losamet in the following countries:


  • Greece

International Drug Name Search

Clorazepaatdikalium PCH




Clorazepaatdikalium PCH may be available in the countries listed below.


Ingredient matches for Clorazepaatdikalium PCH



Dipotassium Clorazepate

Dipotassium Clorazepate is reported as an ingredient of Clorazepaatdikalium PCH in the following countries:


  • Netherlands

International Drug Name Search

Butequine




In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Butequine



Phenylbutazone

Phenylbutazone is reported as an ingredient of Butequine in the following countries:


  • United States

International Drug Name Search

Naphtears




Naphtears may be available in the countries listed below.


Ingredient matches for Naphtears



Naphazoline

Naphazoline is reported as an ingredient of Naphtears in the following countries:


  • Peru

Naphazoline hydrochloride (a derivative of Naphazoline) is reported as an ingredient of Naphtears in the following countries:


  • Chile

International Drug Name Search

Wednesday, September 28, 2016

Zinc Acetate




In the US, Zinc Acetate (zinc acetate systemic) is a member of the drug class minerals and electrolytes and is used to treat Wilson's Disease and Zinc Deficiency.

US matches:

  • Zinc Acetate

Scheme

Ph. Eur.

ATC (Anatomical Therapeutic Chemical Classification)

A16AX05

CAS registry number (Chemical Abstracts Service)

0005970-45-6

Chemical Formula

C4-H6-O4-Zn·2H2O

Molecular Weight

219

Therapeutic Categories

Antiseptic

Astringent agent

Chemical Names

Acetic acid, zinc salt, dihydrate (USP)

Zinc acetate, dihydrate (USP)

Foreign Names

  • Zinci acetas dihydricus (Latin)
  • Zinkacetat-2-Wasser (German)
  • Zinc, acétate de, dihydrate (French)

Generic Names

  • CCRIS 3346 (IS)
  • E 650 (IS)
  • Zinc Acetate (PH: BP 2010, USP 32)
  • Zinc Acetate Dihydrate (PH: Ph. Eur. 6)

Brand Names

  • Climadan Acne (Zinc Acetate andClindamycin)
    Kalbe, Indonesia


  • Galzin
    Gate, United States


  • Juveacne Zinc (Zinc Acetate and Erythromycin)
    Crespal, Peru


  • Polysporin Itch Relief (Zinc Acetate and Pramocaine)
    Johnson & Johnson, Canada


  • ratio-Hemcort-HC (Zinc Acetate and Hydrocortisone)
    ratiopharm, Canada


  • Wilzin
    Orphan, Austria; Orphan, Belgium; Orphan, Germany; Orphan, France; Orphan, United Kingdom; Orphan, Netherlands; Orphan, Poland; Orphan, Slovenia; Orphan, Slovakia; Orphan Europe, Spain; Orphan Europe SARLFR, Denmark


  • Zineryt (Zinc Acetate and Erythromycin)
    Almirall Hermal, Germany; Astellas, Spain; Astellas, United Kingdom; Astellas, South Africa

International Drug Name Search

Glossary

ISInofficial Synonym
PHPharmacopoeia Name
Ph. Eur.European Pharmacopoeia
USPPharmacopoeia of the United States

Click for further information on drug naming conventions and International Nonproprietary Names.

Lormetazepam PCH




Lormetazepam PCH may be available in the countries listed below.


Ingredient matches for Lormetazepam PCH



Lormetazepam

Lormetazepam is reported as an ingredient of Lormetazepam PCH in the following countries:


  • Netherlands

International Drug Name Search

Losan D




Losan D may be available in the countries listed below.


Ingredient matches for Losan D



Hydrochlorothiazide

Hydrochlorothiazide is reported as an ingredient of Losan D in the following countries:


  • Bangladesh

Losartan

Losartan is reported as an ingredient of Losan D in the following countries:


  • Bangladesh

International Drug Name Search

Liduc M




Liduc M may be available in the countries listed below.


Ingredient matches for Liduc M



Pravastatin

Pravastatin sodium salt (a derivative of Pravastatin) is reported as an ingredient of Liduc M in the following countries:


  • Japan

International Drug Name Search

Linipon




Linipon may be available in the countries listed below.


Ingredient matches for Linipon



Risperidone

Risperidone is reported as an ingredient of Linipon in the following countries:


  • Greece

International Drug Name Search

Liberprost




Liberprost may be available in the countries listed below.


Ingredient matches for Liberprost



Bicalutamide

Bicalutamide is reported as an ingredient of Liberprost in the following countries:


  • Argentina

International Drug Name Search

Oxymorphone Tablets



Pronunciation: OX-i-MOR-fone
Generic Name: Oxymorphone
Brand Name: Opana


Oxymorphone is used for:

Treating moderate to severe pain in certain patients.


Oxymorphone is an opioid (narcotic) analgesic. It works by binding to certain receptors in the brain and nervous system to reduce pain.


Do NOT use Oxymorphone if:


  • you are allergic to any ingredient in Oxymorphone or any other codeine- or morphine-related medicine (eg, morphine, codeine, oxycodone)

  • you have difficult or slowed breathing, high levels of carbon dioxide in the blood, or severe asthma, or you are having an asthma attack

  • you are in labor

  • you have moderate to severe liver problems

  • you have severe diarrhea, bowel problems caused by antibiotics or food poisoning, or certain other severe bowel problems (eg, paralytic ileus)

  • you are taking sodium oxybate (GHB) or an agonist/antagonist analgesic (eg, pentazocine)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Oxymorphone:


Some medical conditions may interact with Oxymorphone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of lung or breathing problems (eg, asthma, emphysema, bronchitis, chronic obstructive pulmonary disease [COPD]), sleep apnea (you stop breathing when you sleep), curvature of the spine (eg, kyphoscoliosis), heart problems (eg, cor pulmonale), low blood pressure, dehydration, or low blood volume

  • if you have severe drowsiness, a recent head injury, growths in the brain, increased pressure in the brain, or a history of seizures (eg, epilepsy)

  • if you have liver or kidney problems, gallbladder or pancreas problems, adrenal gland problems (eg, Addison disease), an underactive thyroid, an enlarged prostate, a urinary blockage, or stomach or bowel problems (eg, inflammation), or if you have had recent stomach or bowel surgery.

  • if you drink alcohol regularly, have symptoms of alcohol withdrawal, or have a history of suicidal thoughts or attempts

  • if you have a personal or family history of mental or mood problems, alcohol abuse, or other substance abuse or dependence

  • if you are in poor health or shock, are very overweight, or will be having surgery

Some MEDICINES MAY INTERACT with Oxymorphone. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Phenothiazines (eg, chlorpromazine) because the risk of low blood pressure may be increased

  • Barbiturate anesthetics (eg, thiopental), cimetidine, or sodium oxybate (GHB) because the risk of severe drowsiness, coma, confusion, or slowed or difficult breathing may be increased

  • Anticholinergics (eg, scopolamine, benztropine) because the risk of severe constipation or trouble urinating may be increased

  • Monoamine oxidase inhibitors (MAOIs) (eg, phenelzine) because the risk of a severe reaction including fever, seizures, and coma may be increased

  • Agonist/antagonist analgesics (eg, pentazocine) or naltrexone because they may decrease Oxymorphone's effectiveness and withdrawal may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Oxymorphone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Oxymorphone:


Use Oxymorphone as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Oxymorphone on an empty stomach at least 1 hour before or 2 hours after eating.

  • Oxymorphone must only be taken by mouth.

  • If you are taking Oxymorphone for persistent pain, take it on a regular schedule to help control the pain more effectively.

  • Do not change your dose or suddenly stop taking Oxymorphone without checking with your doctor.

  • If Oxymorphone is no longer needed, dispose of it as soon as possible. Ask your doctor or pharmacist how to dispose of Oxymorphone properly.

  • If you miss a dose of Oxymorphone and you are taking it regularly, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Oxymorphone.



Important safety information:


  • Oxymorphone may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol, other opiate pain medicines, or certain other medicines. Use Oxymorphone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you take Oxymorphone; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Oxymorphone may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

  • Oxymorphone may be habit forming. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Misuse or abuse of Oxymorphone may cause severe side effects, including severe breathing problems, seizures, coma, and possibly death.

  • Constipation is a common side effect of Oxymorphone. Talk to your doctor about using laxatives or stool softeners to prevent or treat constipation while you use Oxymorphone.

  • If your pain continues or becomes worse or if you have side effects that concern you, contact your doctor.

  • Tell your doctor or dentist that you take Oxymorphone before you receive any medical or dental care, emergency care, or surgery.

  • Use Oxymorphone with caution in the ELDERLY; they may be more sensitive to its effects, especially drowsiness, dizziness, confusion, and nausea.

  • Oxymorphone should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Oxymorphone may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Oxymorphone while you are pregnant. It is unknown if Oxymorphone is found in breast milk. Do not breast-feed while taking Oxymorphone.

When used for long periods of time or at high doses, Oxymorphone may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Oxymorphone stops working well. Do not take more than prescribed.


Some people who use Oxymorphone for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. Dependence is unlikely to be an issue in terminally ill patients where comfort is more important. If you are taking Oxymorphone regularly, do not suddenly stop taking it without checking with your doctor. WITHDRAWAL symptoms have occurred when Oxymorphone is suddenly stopped and may include anxiety; diarrhea; fever, runny nose, or sneezing; goose bumps and abnormal skin sensations; nausea and vomiting; pain; rigid muscles; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; and trouble sleeping. Contact your doctor if you notice any of these symptoms after stopping Oxymorphone.



Possible side effects of Oxymorphone:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Anxiety; constipation; dizziness; drowsiness; dry mouth; gas; headache; lightheadedness; nausea; sweating; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; fainting; fast, slow, or irregular heartbeat; fever; hallucinations; mental or mood changes; seizure; severe or persistent dizziness or drowsiness; severe or persistent headache or vomiting; shallow, slowed, or difficult breathing; trouble urinating; unusual swelling; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Oxymorphone side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include bluish skin; chest pain; cold and clammy skin; coma; difficult or slow breathing; limp muscles; numbness of an arm or leg; pinpoint pupils; severe drowsiness or dizziness; slow or irregular heartbeat.


Proper storage of Oxymorphone:

Store Oxymorphone at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store Oxymorphone in the bathroom. Keep Oxymorphone out of the reach of children and away from pets.


General information:


  • If you have any questions about Oxymorphone, please talk with your doctor, pharmacist, or other health care provider.

  • Oxymorphone is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Oxymorphone. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Oxymorphone resources


  • Oxymorphone Side Effects (in more detail)
  • Oxymorphone Dosage
  • Oxymorphone Use in Pregnancy & Breastfeeding
  • Drug Images
  • Oxymorphone Drug Interactions
  • Oxymorphone Support Group
  • 107 Reviews for Oxymorphone - Add your own review/rating


Compare Oxymorphone with other medications


  • Labor Pain
  • Pain

Lenistar




Lenistar may be available in the countries listed below.


Ingredient matches for Lenistar



Butamirate

Butamirate citrate (a derivative of Butamirate) is reported as an ingredient of Lenistar in the following countries:


  • Italy

International Drug Name Search

Tuesday, September 27, 2016

Labetalol




In the US, Labetalol (labetalol systemic) is a member of the drug class non-cardioselective beta blockers and is used to treat High Blood Pressure, Hypertensive Emergency, Mitral Valve Prolapse and Pheochromocytoma.

US matches:

  • Labetalol

  • Labetalol Tablets

  • Labetalol Intravenous

  • Labetalol Hydrochloride

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C07AG01

CAS registry number (Chemical Abstracts Service)

0036894-69-6

Chemical Formula

C19-H24-N2-O3

Molecular Weight

328

Therapeutic Categories

ß-Adrenergic blocking agent

α-Adrenergic blocking agent

Chemical Name

Benzamide, 2-hydroxy-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]-

Foreign Names

  • Labetalolum (Latin)
  • Labetalol (German)
  • Labétalol (French)
  • Labetalol (Spanish)

Generic Names

  • Labetalol (OS: BAN)
  • Labétalol (OS: DCF)
  • Labetalolo (OS: DCIT)
  • AH 5158 (IS)
  • Ibidomide (IS)
  • Sch 15719 (IS)
  • Labetalol Hydrochloride (OS: BANM, USAN, JAN)
  • AH 5158 A (IS: AllenHanbury)
  • Sch 15719 W (IS: Schering)
  • Labétalol (chlorhydrate de) (PH: Ph. Eur. 6)
  • Labetalol Hydrochloride (PH: BP 2010, Ph. Eur. 6, USP 32)
  • Labetalolhydrochlorid (PH: Ph. Eur. 6)
  • Labetaloli hydrochloridum (PH: Ph. Eur. 6)

Brand Names

  • Trandate
    GlaxoSmithKline, Denmark; GlaxoSmithKline, Tunisia


  • Albetol
    Leiras, Finland


  • Apo-Labetalol
    Apotex, Canada


  • Ascool
    Towa Yakuhin, Japan


  • Biascor
    Biol, Argentina


  • Hybloc
    Pacific, New Zealand


  • Ipolab
    Medifarma, Italy


  • Labetalol HCL Actavis
    Actavis, Netherlands


  • Labetalol HCl CF
    Centrafarm, Netherlands


  • Labetalol HCl Katwijk
    Apotex Europe, Netherlands


  • Labetalol HCl Merck
    Mylan, Netherlands


  • Labetalol HCl PCH
    Pharmachemie, Netherlands


  • Labetalol HCl ratiopharm
    ratiopharm, Netherlands


  • Labetalol HCl Sandoz
    Sandoz, Netherlands


  • Labetalol Hydrochloride Injection
    Akorn, United States; Apotex, United States; Bedford, United States; Mayne, United States


  • Labetalol Hydrochloride
    Apotex, United States; Hospira, United States; Mayne, Hong Kong; Sagent Pharmaceuticals, United States; Sandoz, Canada; Sandoz, United States; Taylor, United States; Teva USA, United States; UDL, United States; Watson, United States


  • Labetalol Shanghai No.1
    Shanghai No.1, China


  • Labetalol
    Generics, Malta; Remedica, Cyprus


  • Presolol
    Alphapharm, Australia; Alphapharm, Taiwan


  • Resporito
    Tsuruhara Seiyaku, Japan


  • Trandate
    GlaxoSmithKline, United Arab Emirates; GlaxoSmithKline, Austria; GlaxoSmithKline, Belgium; GlaxoSmithKline, Bahrain; GlaxoSmithKline, Switzerland; GlaxoSmithKline, Chile; GlaxoSmithKline, Cyprus; GlaxoSmithKline, Denmark; GlaxoSmithKline, Estonia; GlaxoSmithKline, France; GlaxoSmithKline, Israel; GlaxoSmithKline, Iran; GlaxoSmithKline, Iceland; GlaxoSmithKline, Jordan; GlaxoSmithKline, Japan; GlaxoSmithKline, Kuwait; GlaxoSmithKline, Lebanon; GlaxoSmithKline, Luxembourg; GlaxoSmithKline, Netherlands; GlaxoSmithKline, Norway; GlaxoSmithKline, New Zealand; GlaxoSmithKline, Oman; GlaxoSmithKline, Qatar; GlaxoSmithKline, Sweden; GlaxoSmithKline, Singapore; GlaxoSmithKline, Syria; GlaxoSmithKline, Taiwan; GlaxoSmithKline, Yemen; GlaxoSmithKline, South Africa; Kern, Spain; Paladin, Canada; Prometheus, United States; Sigma, Australia; Sigma, Hong Kong; Teofarma, Italy; UCB, Ireland; UCB Pharma, United Kingdom

International Drug Name Search

Glossary

BANBritish Approved Name
BANMBritish Approved Name (Modified)
DCFDénomination Commune Française
DCITDenominazione Comune Italiana
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Lacryvisc SE




Lacryvisc SE may be available in the countries listed below.


Ingredient matches for Lacryvisc SE



Carbomer

Carbomer is reported as an ingredient of Lacryvisc SE in the following countries:


  • Switzerland

International Drug Name Search

Losaprol




Losaprol may be available in the countries listed below.


Ingredient matches for Losaprol



Omeprazole

Omeprazole is reported as an ingredient of Losaprol in the following countries:


  • Brazil

International Drug Name Search

Bascul




Bascul may be available in the countries listed below.


Ingredient matches for Bascul



Sulfamethoxazole

Sulfamethoxazole is reported as an ingredient of Bascul in the following countries:


  • Peru

Trimethoprim

Trimethoprim is reported as an ingredient of Bascul in the following countries:


  • Peru

International Drug Name Search

Lormine




Lormine may be available in the countries listed below.


Ingredient matches for Lormine



Dexamethasone

Dexamethasone is reported as an ingredient of Lormine in the following countries:


  • Argentina

International Drug Name Search

Clear Away




Ingredient matches for Clear Away



Salicylic Acid

Salicylic Acid is reported as an ingredient of Clear Away in the following countries:


  • United States

International Drug Name Search

Tildiem




Tildiem may be available in the countries listed below.


UK matches:

  • Tildiem LA 200, Tildiem LA 300 (SPC)
  • Tildiem Retard 90mg, Tildiem Retard 120mg (SPC)
  • Tildiem Tablets 60mg (SPC)

Ingredient matches for Tildiem



Diltiazem

Diltiazem is reported as an ingredient of Tildiem in the following countries:


  • Chile

  • Tunisia

Diltiazem hydrochloride (a derivative of Diltiazem) is reported as an ingredient of Tildiem in the following countries:


  • Belgium

  • France

  • Greece

  • Ireland

  • Italy

  • Luxembourg

  • Netherlands

  • Oman

  • Switzerland

  • United Kingdom

  • Vietnam

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Lotagen




Lotagen may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Lotagen



Policresulen

Policresulen is reported as an ingredient of Lotagen in the following countries:


  • Australia

  • Austria

  • France

  • Germany

  • Italy

  • South Africa

  • Switzerland

International Drug Name Search

Themigrel




Themigrel may be available in the countries listed below.


Ingredient matches for Themigrel



Clopidogrel

Clopidogrel hydrogen sulfate (a derivative of Clopidogrel) is reported as an ingredient of Themigrel in the following countries:


  • Sri Lanka

International Drug Name Search

Lorzaar Orifarm




Lorzaar Orifarm may be available in the countries listed below.


Ingredient matches for Lorzaar Orifarm



Losartan

Losartan potassium salt (a derivative of Losartan) is reported as an ingredient of Lorzaar Orifarm in the following countries:


  • Denmark

International Drug Name Search

Lactapen G




Lactapen G may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Lactapen G



Benzylpenicillin

Benzylpenicillin procaine (a derivative of Benzylpenicillin) is reported as an ingredient of Lactapen G in the following countries:


  • New Zealand

International Drug Name Search

Monday, September 26, 2016

Loron




Loron may be available in the countries listed below.


UK matches:

  • Loron
  • Loron 520 (SPC)

Ingredient matches for Loron



Clodronic Acid

Clodronic Acid disodium tetrahydrate (a derivative of Clodronic Acid) is reported as an ingredient of Loron in the following countries:


  • United Kingdom

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Leuprorelin Sandoz




Leuprorelin Sandoz may be available in the countries listed below.


Ingredient matches for Leuprorelin Sandoz



Leuprorelin

Leuprorelin acetate (a derivative of Leuprorelin) is reported as an ingredient of Leuprorelin Sandoz in the following countries:


  • Switzerland

International Drug Name Search

Lipirate




Lipirate may be available in the countries listed below.


Ingredient matches for Lipirate



Fenofibrate

Fenofibrate is reported as an ingredient of Lipirate in the following countries:


  • Vietnam

International Drug Name Search

Laclorhex




Laclorhex may be available in the countries listed below.


Ingredient matches for Laclorhex



Chlorhexidine

Chlorhexidine digluconate (a derivative of Chlorhexidine) is reported as an ingredient of Laclorhex in the following countries:


  • Argentina

International Drug Name Search

Fluorcalcic




Fluorcalcic may be available in the countries listed below.


Ingredient matches for Fluorcalcic



Sodium Fluoride

Sodium Fluoride is reported as an ingredient of Fluorcalcic in the following countries:


  • Czech Republic

International Drug Name Search

Lacril




Lacril may be available in the countries listed below.


Ingredient matches for Lacril



Methylcellulose

Methylcellulose is reported as an ingredient of Lacril in the following countries:


  • Denmark

International Drug Name Search

Lacovin




Lacovin may be available in the countries listed below.


Ingredient matches for Lacovin



Minoxidil

Minoxidil is reported as an ingredient of Lacovin in the following countries:


  • Spain

International Drug Name Search

Loricid




Loricid may be available in the countries listed below.


Ingredient matches for Loricid



Allopurinol

Allopurinol is reported as an ingredient of Loricid in the following countries:


  • Philippines

International Drug Name Search

Lormetazepam Alter




Lormetazepam Alter may be available in the countries listed below.


Ingredient matches for Lormetazepam Alter



Lormetazepam

Lormetazepam is reported as an ingredient of Lormetazepam Alter in the following countries:


  • Italy

International Drug Name Search

Friday, September 23, 2016

Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol


Pronunciation: a-SEE-tik AS-id/AN-tee-PYE-reen/BEN-zoe-kane/POL-ee-COHS-an-ol
Generic Name: Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol
Brand Name: PR Otic


Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol is used for:

Relieving pain and inflammation in the ear caused by certain ear conditions. It may be used with antibiotics given by mouth to treat certain ear infections. It may also be used to help remove a buildup of earwax.


Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol is an antibacterial, analgesic, and anesthetic combination. It works by relieving pressure and reducing inflammation, congestion, pain, and discomfort.


Do NOT use Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol if:


  • you are allergic to any ingredient in Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol or to similar medicines

  • your eardrum is perforated or you have discharge from your ear

Contact your doctor or health care provider right away if any of these apply to you.



Before using Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol:


Some medical conditions may interact with Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol. However, no specific interactions with Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol are known at this time.


Ask your health care provider if Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol:


Use Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol is for topical use in the ear canal only. Do not get Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol in the eyes, nose, or mouth. If you get Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol in any of these areas, rinse right away with cool water.

  • Before using, hold the ear drop container in your hand for 1 or 2 minutes to avoid dizziness that may result from putting cold drops into the ear. To use ear drops, lie down or tilt your head so that the affected ear faces up. For adults, gently pull the earlobe up and back to straighten the ear canal. For children, gently pull the earlobe down and back to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for several minutes so the medicine can run to the bottom of the ear canal. Moisten a clean cotton plug with Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol and gently insert into the ear canal to prevent medicine from leaking out.

  • To prevent germs from contaminating the medicine, do not touch the applicator to any surface, including the ear. Do not rinse dropper after use. Keep the container tightly closed.

  • If Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol is brown or contains particles, do not use it.

  • If you miss a dose of Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol.



Important safety information:


  • Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol while you are pregnant. It is not known if Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol is found in breast milk. If you are or will be breast-feeding while you use Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol:


All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol. Seek medical attention right away if any of these SEVERE side effects occur:



Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); irritation not present when you began using Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch .



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol:

Store Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Protect from freezing. Keep the container tightly closed. Store away from heat, moisture, and light. Keep Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol out of the reach of children and away from pets.


General information:


  • If you have any questions about Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol, please talk with your doctor, pharmacist, or other health care provider.

  • Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol resources


  • Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol Use in Pregnancy & Breastfeeding
  • Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol Support Group
  • 0 Reviews for Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol - Add your own review/rating


Compare Acetic Acid/Antipyrine/Benzocaine/U-Polycosanol with other medications


  • Ear Wax Impaction

Hexatron




Hexatron may be available in the countries listed below.


Ingredient matches for Hexatron



Tranexamic Acid

Tranexamic Acid is reported as an ingredient of Hexatron in the following countries:


  • Japan

International Drug Name Search

Nithiodote


Generic Name: sodium nitrite and sodium thiosulfate (Intravenous route)


SOE-dee-um NYE-trite, SOE-dee-um thye-oh-SUL-fate


Intravenous route(Solution)

Sodium nitrite can cause serious adverse reactions and death from hypotension and methemoglobin formation, even at doses less than twice the recommended therapeutic dose. Hypotension and methemoglobin formation can occur concurrently or separately. Patients should be closely monitored to ensure adequate perfusion and oxygenation during treatment with sodium nitrite. Alternative therapeutic approaches should be considered in patients known to have diminished oxygen or cardiovascular reserve and in those at higher risk of developing methemoglobinemia .



Commonly used brand name(s)

In the U.S.


  • Nithiodote

Available Dosage Forms:


  • Solution

Uses For Nithiodote


Sodium nitrite and sodium thiosulfate injection are used together to treat cyanide poisoning. Cyanide poisoning is a life-threatening condition that requires immediate medical attention.


This medicine is to be given only by or under the direct supervision of a doctor.


Before Using Nithiodote


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of sodium nitrite and sodium thiosulfate injection in the pediatric population. However, because cyanide poisoning is a life-threatening condition, it is used in the pediatric population. Recommended doses should not be exceeded, and the patient should be carefully monitored during treatment.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sodium nitrite and sodium thiosulfate injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving sodium nitrite and sodium thiosulfate injection.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Anemia or

  • Carbon monoxide poisoning or

  • Glucose-6-phosphate dehydrogenase (G6PD) deficiency (genetic disorder affecting red blood cells) or

  • Heart disease or

  • Lung or breathing problems (eg, asthma, chronic obstructive pulmonary disease) or

  • Smoke inhalation injury—Use with caution. May cause side effects to become worse.

  • Hypotension (low blood pressure)—Use with caution. May make this condition worse.

  • Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of Nithiodote


A nurse or other trained health professional will give you or your child this medicine in a hospital. This medicine is given through a needle placed in one of your veins.


Precautions While Using Nithiodote


Your doctor will check your or your child's progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly. Blood tests will also be needed to check for unwanted effects.


Severe hypotension (low blood pressure) may occur with this medicine. It could be life-threatening and requires immediate medical attention. Your doctor will measure your blood pressure and keep it from going too low while you are receiving this medicine.


This medicine may cause a rare, but serious blood problem called methemoglobinemia. Newborn babies and infants may be more likely to have this serious side effect. Your doctor will measure how much methemoglobin is in your blood and keep it from going too high while you are receiving this medicine.


Nithiodote Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor or nurse immediately if any of the following side effects occur:


Incidence not known
  • Bluish color of the fingernails, lips, skin, palms, or nail beds

  • blurred vision

  • change in consciousness

  • confusion

  • dark urine

  • difficult or labored breathing

  • dizziness

  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

  • drowsiness

  • fainting

  • fast, slow, pounding, or irregular heartbeat or pulse

  • fever

  • headache

  • lightheadedness

  • loss of consciousness

  • nausea

  • numbness and tingling sensation

  • pale skin

  • rapid heart rate

  • rapid shallow breathing

  • seizures

  • shortness of breath

  • sore throat

  • sweating

  • tightness in the chest

  • troubled breathing

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • vomiting

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Incidence not known
  • Abdominal or stomach pain

  • anxiety

  • confusion about identity, place, and time

  • headache

  • hives or welts

  • increased sweating

  • itching

  • redness of the skin

  • salty taste in your mouth

  • skin rash

  • tingling sensation at the injection site

  • warm sensation over your body

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Losartan Atid




Losartan Atid may be available in the countries listed below.


Ingredient matches for Losartan Atid



Losartan

Losartan potassium salt (a derivative of Losartan) is reported as an ingredient of Losartan Atid in the following countries:


  • Germany

International Drug Name Search

Neo Mercazole




Neo-Mercazole may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Neo-Mercazole



Carbimazole

Carbimazole is reported as an ingredient of Neo-Mercazole in the following countries:


  • Australia

  • Denmark

  • India

  • Indonesia

  • Ireland

  • New Zealand

  • Norway

  • Oman

  • United Kingdom

International Drug Name Search

Fedrin




Fedrin may be available in the countries listed below.


Ingredient matches for Fedrin



Ephedrine

Ephedrine hydrochloride (a derivative of Ephedrine) is reported as an ingredient of Fedrin in the following countries:


  • Bangladesh

International Drug Name Search

Lacrybiotic




Lacrybiotic may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Lacrybiotic



Chloramphenicol

Chloramphenicol is reported as an ingredient of Lacrybiotic in the following countries:


  • France

International Drug Name Search

Infection Prophylaxis Medications


Drugs associated with Infection Prophylaxis

The following drugs and medications are in some way related to, or used in the treatment of Infection Prophylaxis. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.





Drug List:

Loperamide HCl Hexal




Loperamide HCl Hexal may be available in the countries listed below.


Ingredient matches for Loperamide HCl Hexal



Loperamide

Loperamide hydrochloride (a derivative of Loperamide) is reported as an ingredient of Loperamide HCl Hexal in the following countries:


  • Netherlands

International Drug Name Search

Lacdigest




Lacdigest may be available in the countries listed below.


Ingredient matches for Lacdigest



Tilactase

Tilactase is reported as an ingredient of Lacdigest in the following countries:


  • Italy

  • Switzerland

International Drug Name Search

Thursday, September 22, 2016

Laroxyl




Laroxyl may be available in the countries listed below.


Ingredient matches for Laroxyl



Amitriptyline

Amitriptyline is reported as an ingredient of Laroxyl in the following countries:


  • Botswana

  • Ghana

  • Kenya

  • Malawi

  • Mauritius

  • Namibia

  • Nigeria

  • Sudan

  • Tanzania

  • Uganda

  • Zambia

  • Zimbabwe

Amitriptyline hydrochloride (a derivative of Amitriptyline) is reported as an ingredient of Laroxyl in the following countries:


  • France

  • Italy

  • Taiwan

  • Turkey

International Drug Name Search

Lipotropic




Lipotropic may be available in the countries listed below.


Ingredient matches for Lipotropic



Atorvastatin

Atorvastatin is reported as an ingredient of Lipotropic in the following countries:


  • Chile

  • Peru

International Drug Name Search

Dilatrate-SR


Dilatrate-SR is a brand name of isosorbide dinitrate, approved by the FDA in the following formulation(s):


DILATRATE-SR (isosorbide dinitrate - capsule, extended release; oral)



  • Manufacturer: SCHWARZ PHARMA

    Approval date: September 2, 1988

    Strength(s): 40MG [RLD]

Has a generic version of Dilatrate-SR been approved?


No. There is currently no therapeutically equivalent version of Dilatrate-SR available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Dilatrate-SR. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents

There are no current U.S. patents associated with Dilatrate-SR.

See also...

  • Dilatrate-SR Consumer Information (Wolters Kluwer)
  • Dilatrate-SR Consumer Information (Cerner Multum)
  • Dilatrate-SR Advanced Consumer Information (Micromedex)
  • Isosorbide Dinitrate Consumer Information (Wolters Kluwer)
  • Isosorbide Dinitrate Extended-Release Consumer Information (Wolters Kluwer)
  • Isosorbide dinitrate Consumer Information (Cerner Multum)
  • Apo-Isdn Advanced Consumer Information (Micromedex)
  • Isosorbide dinitrate Oral, Sublingual Advanced Consumer Information (Micromedex)

Leukocytosis Medications


There are currently no drugs listed for "Leukocytosis". See Blood Disorders.

Definition of Leukocytosis: An abnormally large increase in the number of white blood cells in the blood, often occurring during an acute infection or inflammation.





Drug List:

Estring


Generic Name: estrogen (Vaginal route)


Commonly used brand name(s)

In the U.S.


  • Estrace

  • Estring

  • Femring

  • Ortho Dienestrol

  • Premarin

  • Vagifem

In Canada


  • Estragyn

  • Neo-Estrone

  • Oestrilin

Available Dosage Forms:


  • Tablet

  • Cream

  • Insert, Extended Release

  • Suppository

Uses For Estring


Estrogens are hormones produced by the body. Among other things, estrogens help develop and maintain female organs.


When your body is in short supply of this hormone, replacing it can ease the uncomfortable changes that occur in the vagina, vulva (female genitals), and urethra (part of the urinary system). Conditions that are treated with vaginal estrogens include a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis).


Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens:


  • Dryness and soreness in the vagina

  • Itching, redness, or soreness of the vulva

  • Feeling an urge to urinate more often then is needed or experiencing pain while urinating

  • Pain during sexual intercourse

When used vaginally or on the skin, most estrogens are absorbed into the bloodstream and cause some, but not all, of the same effects as when they are taken by mouth. Estrogens used vaginally at very low doses for treating local problems of the genitals and urinary system will not protect against osteoporosis or stop the hot flushes caused by menopause.


Estrogens for vaginal use are available only with your doctor's prescription.


Before Using Estring


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Estrogen vaginal cream is not indicated in children. Studies have not been conducted.


Geriatric


Elderly women greater than 65 years of age may have an increased risk of certain side effects during treatment, especially stroke, invasive breast cancer, and memory problems.


Pregnancy


Estrogens should not be used during pregnancy, since an estrogen called diethylstilbestrol (DES) that is no longer taken for hormone replacement has caused serious birth defects in humans and animals.


Breast Feeding


Use of this medicine is not recommended in nursing mothers. Estrogens pass into the breast milk and may decrease the amount and quality of breast milk. Caution should be exercised in mothers who are using estrogen and breast-feeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:


  • Asthma or

  • Epilepsy or

  • Heart problems or

  • Kidney problems or

  • Migraine headaches—Estrogens may worsen these conditions.

  • Blood clotting problems—Although worsening of a blood clotting condition is unlikely, some doctors do not prescribe vaginal estrogens for patients with blood clotting problems or a history of these problems.

  • Breast cancer (active, suspected, or past history)—Estrogens should not be used.

  • Certain cancers, including cancers of the breast, bone, or uterus (active or suspected)—Estrogens may interfere with the treatment of breast or bone cancer or worsen cancer of the uterus when these conditions are present.

  • Cholestatic jaundice (flow of bile from the liver is blocked), past history—Caution should be used when this condition is present.

  • Diabetes mellitus (sugar diabetes)—Estrogens may alter your body's response to sugar in your diet.

  • Endometriosis or

  • Fibroid tumors of the uterus—Estrogens may worsen endometriosis or increase the size of fibroid tumors.

  • Gallbladder problems (gallstones)—Estrogens may increase your chance of getting a gallbladder attack.

  • Heart attack or

  • Stroke (active or past history)—Estrogens should not be used.

  • Hepatic hemangioma (noncancerous tumors of the liver)—Estrogens may worsen this medical problem.

  • High blood pressure—Estrogens may worsen this medical problem.

  • Hypercalcemia (too much calcium in your blood)—Estrogens may worsen this medical problem.

  • Hypertriglyceridemia (too much triglycerides in your blood)—Estrogens may increase your chance of getting pancreatitis or other side effects.

  • Hypocalcemia (too little calcium in your blood)—Your doctor should treat the low calcium in your blood before starting estrogen therapy.

  • Irritation or infection of the vagina—Usually estrogens decrease infections or irritation of the vagina, but sometimes these conditions may become worse.

  • Liver disease or

  • Liver problems—Estrogens should not be used.

  • Lupus erythematosus, systemic (SLE or lupus)—Estrogens may worsen this medical problem.

  • Physical problems within the vagina, such as narrow vagina, vaginal stenosis, or vaginal prolapse—Estradiol vaginal insert or ring may be more likely to slip out of place or cause problems, such as irritation of the vagina.

  • Porphyria—Estrogens may worsen this medical problem.

  • Thyroid problems (underactive thyroid)—Estrogens may alter your body's response to your thyroid medication. Your doctor may alter the amount of thyroid replacement that you take while on estrogen therapy.

  • Vision changes, sudden onset including

  • Bulging eyes or

  • Double vision or

  • Migraine headache or

  • Vision loss, partial or complete—Estrogens may cause these problems. Tell your doctor if you have had any of these problems.

  • Unusual genital or vaginal bleeding of unknown causes—Use of estrogens may delay diagnosis or worsen the condition. The reason for the bleeding should be determined before estrogens are used.

Proper Use of estrogen

This section provides information on the proper use of a number of products that contain estrogen. It may not be specific to Estring. Please read with care.


Vaginal estrogen products usually come with patient directions. Read them carefully before using this medicine.


Wash your hands before and after using the medicine. Also, keep the medicine out of your eyes. If this medicine does get into your eyes, wash them out immediately, but carefully, with large amounts of tap water. If your eyes still burn or are painful, check with your doctor.


Use this medicine only as directed. Do not use more of it and do not use it for a longer time than your doctor ordered. It can take up to 4 months to see the full effect of the estrogens. Your doctor may reconsider continuing your estrogen treatment or may lower your dose several times within the first one or two months, and every 3 to 6 months after that. Sometimes a switch to oral estrogens may be required for added benefits or for higher doses. When using the estradiol vaginal insert or ring, you will need to replace it every 3 months or remove it after 3 months.


For vaginal creams or suppositories:


  • Vaginal creams and some vaginal suppositories are inserted with a plastic applicator. Directions for using the applicator are supplied with your medicine. If you do not see your dose marked on the applicator, ask your health care professional for more information.

  • To fill the applicator for cream dosage forms:
    • Screw the applicator onto the tube.

    • Squeeze the medicine into the applicator slowly until it is measured properly.

    • Remove the applicator from the tube. Replace the cap on the tube.


  • To fill the applicator for suppository dosage form:
    • Place the suppository into the applicator.


  • To place the dose using the applicator for cream and suppository dosage forms:
    • Relax while lying on your back with your knees bent or stand with one foot on a chair.

    • Hold the full applicator in one hand. Slide the applicator slowly into the vagina. Stop before it becomes uncomfortable.

    • Slowly press the plunger until it stops.

    • Withdraw the applicator. The medicine will be left behind in the vagina.


  • To care for the applicator for cream and suppository dosage forms:
    • Clean the applicator after use by pulling the plunger out of the applicator and washing both parts completely in warm, soapy water. Do not use hot or boiling water.

    • Rinse well.

    • After drying the applicator, replace the plunger.


For vaginal insert or ring dosage form:


  • To place the vaginal insert:
    • Relax while lying on your back with your knees bent or stand with one foot on a chair.

    • Pinch or press the sides of the vaginal insert together, between your forefinger and middle finger.

    • With one hand, part the folds of skin around your vagina.

    • Slide the vaginal insert slowly into the upper third of your vagina. Stop before it becomes uncomfortable. The exact location is not too important but it should be comfortable.

    • If it seems uncomfortable, then carefully push the vaginal insert higher into the vagina.


  • To remove the vaginal insert:
    • Stand with one foot on a chair.

    • Slide one finger into the vagina and hook it around the closest part of the vaginal insert.

    • Slowly pull the vaginal insert out.

    • Dispose of the vaginal insert by wrapping it up and throwing it into the trash. Do not flush it down the toilet.


Dosing


The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For conjugated estrogens

  • For vaginal dosage form (cream):
    • For treating inflammation of the vagina (atrophic vaginitis):
      • Adults—At first, 0.5 gram (g) of conjugated estrogens inserted into the vagina once a day or as directed by your doctor to achieve the lowest dose possible. Usually your doctor will want you to use this medicine for only three weeks of each month (three weeks on and one week off). Your doctor may increase your dose as needed. However, the dose is usually not more than 2 grams per day.


    • For treating a genital skin condition (vulvar atrophy):

    • Adults—0.5 gram (g) of conjugated estrogens inserted into the vagina two times per week. Usually your doctor will want you to use this medicine for only three weeks of each month (three weeks on and one week off).


  • For estradiol

  • For vaginal dosage form (cream):
    • For treating a genital skin condition (vulvar atrophy) and inflammation of the vagina (atrophic vaginitis):
      • Adults—200 to 400 micrograms (mcg) of estradiol (two to four grams of cream) inserted into the vagina once a day for one to two weeks, decreasing the dose by one half over two and four weeks. After four weeks, your doctor will probably ask you to use the medicine less often, such as 100 mcg (one gram of cream) one to three times a week and for only three weeks of each month (three weeks on and one week off).



  • For vaginal dosage form (insert or ring):
    • For treating a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis) in postmenopausal women, and inflammation of the urethra (urethritis) in postmenopausal women:
      • Adults—One insert containing 2 to 24.8 milligrams (mg) of estradiol inserted into the vagina every three months. The insert will slowly release estradiol at a rate of 7.5 to 100 micrograms (mcg) every twenty-four hours with continuous use.



  • For estrone

  • For vaginal dosage form (cream):
    • For treating a genital skin condition (vulvar atrophy) and inflammation of the vagina (atrophic vaginitis) in postmenopausal women:
      • Adults—2 to 4 milligrams (mg) of estrone (two to four grams of cream) inserted into the vagina once a day or as directed by your doctor.



  • For vaginal dosage form (suppository):
    • For treating a genital skin condition (vulvar atrophy) and inflammation of the vagina (atrophic vaginitis) in postmenopausal women:
      • Adults—250 to 500 micrograms (mcg) inserted into the vagina once a day or as directed by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


When using the suppository or cream several times a week: If you miss a dose of this medicine and remember it within 1 or 2 days of the missed dose, use the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


When using the cream or suppositories more than several times a week: If you miss a dose of this medicine, use it as soon as possible if remembered within 12 hours of the missed dose. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Keep out of the reach of children.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using Estring


It is very important that your doctor check your progress at regular visits to make sure this medicine does not cause unwanted effects. Plan on going to see your doctor every year, but some doctors require visits more often.


It is not yet known whether the use of vaginal estrogens increases the risk of breast cancer in women. It is very important that you check your breasts on a regular basis for any unusual lumps or discharge. Report any problems to your doctor. You should also have a mammogram (x-ray picture of the breasts) done if your doctor recommends it.


It is important that you have a regular pelvic exam (pap smear). Your doctor will tell you how often this exam should be done.


Talk to your doctor if you have high blood pressure, high cholesterol (fats in the blood), or diabetes, use tobacco, or are overweight. You may have a higher risk for getting heart disease.


Although the chance is low, use of estrogen may increase your chance of getting cancer of the ovary or uterus (womb). Regular visits to your health professional can help identify these serious side effects early.


If you think that you may be pregnant, stop using the medicine immediately and check with your doctor.


Tell the doctor in charge that you are using this medicine before having any laboratory test, because some test results may be affected.


For vaginal creams or suppositories:


  • Avoid using latex condoms, diaphragms, or cervical caps for up to 72 hours after using estrogen vaginal creams. Certain estrogen products may contain oils in the creams that can weaken latex (rubber) products and cause condoms to break or leak, or cervical caps or diaphragms to wear out sooner. Check with your health care professional to make sure the vaginal estrogen product you are using can be used with latex devices.

  • This medicine is often used at bedtime to increase effectiveness through better absorption.

  • Vaginal creams or suppositories will melt and leak out of the vagina. A minipad or sanitary napkin will protect your clothing. Do not use tampons (like those used for menstrual periods) since they may soak up the medicine and make the medicine less effective.

  • Avoid exposing your male sexual partner to your vaginal estrogen cream or suppository by not having sexual intercourse right after using these medicines. Your male partner might absorb the medicine through his penis if it comes in contact with the medicine.

For estradiol vaginal inserts or rings:


  • Contact your doctor if you have problems removing your vaginal insert.

  • It is not necessary to remove the vaginal insert for sexual intercourse unless you prefer to remove it.

  • If you do take it out, or if it accidentally slips or comes out of the vagina, you can replace the vaginal insert in the vagina after washing it with lukewarm water. Never use hot or boiling water.

  • If it slips down, gently push it upwards and back into place.

  • Replace the vaginal insert every 3 months.

  • Talk to your doctor on a regular basis about how long to use the vaginal insert.

Estring Side Effects


The risk of any serious adverse effect is unlikely for most women using low doses of estrogens vaginally. Even women with special risks have used vaginal estrogens without problems.


Check with your doctor immediately if any of the following side effects occur:


Less common
  • Breast pain

  • enlarged breasts

  • itching of the vagina or genitals

  • headache

  • nausea

  • stinging or redness of the genital area

  • thick, white vaginal discharge without odor or with a mild odor

Rare
  • Feeling of vaginal pressure (with estradiol vaginal insert or ring)

  • unusual or unexpected uterine bleeding or spotting

  • vaginal burning or pain (with estradiol vaginal insert or ring)

Incidence not known
  • Diarrhea

  • dizziness

  • fast heartbeat

  • feeling faint

  • fever

  • hives

  • hoarseness

  • itching

  • joint pain, stiffness, or swelling

  • muscle pain

  • rash

  • shortness of breath

  • skin redness

  • swelling of eyelids, face, lips, hands, or feet

  • tightness in the chest

  • trouble with breathing or swallowing

  • vomiting

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • Abdominal or back pain

  • clear vaginal discharge (usually means the medicine is working)

Incidence not known
  • Acne

  • enlargement of penis or testes

  • growth of pubic hair

  • rapid increase in height

  • swelling of the breasts or breast soreness in males

Also, many women who are using estrogens with a progestin (another female hormone) will start having monthly vaginal bleeding that is similar to menstrual periods. This effect will continue for as long as the medicine is taken. However, monthly bleeding will not occur in women who have had the uterus removed by surgery (hysterectomy).


Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



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Cervoxan




Cervoxan may be available in the countries listed below.


Ingredient matches for Cervoxan



Vinburnine

Vinburnine is reported as an ingredient of Cervoxan in the following countries:


  • France

  • Portugal

  • Spain

International Drug Name Search

Albucid




Albucid may be available in the countries listed below.


Ingredient matches for Albucid



Sulfacetamide Sodium

Sulfacetamide sodium salt (a derivative of Sulfacetamide) is reported as an ingredient of Albucid in the following countries:


  • India

  • Indonesia

International Drug Name Search

Cream of Magnesia B.P. (Boots Company plc)






Boots Cream of Magnesia B.P.



(Magnesium Oxide, Magnesium Sulphate)



Relieves constipation



Relieves acid indigestion



e 200 ml



Read all of this label for full instructions.




What this medicine is for


This effective formulation contains an antacid to neutralise excess acid and relieve indigestion. It also contains a laxative to relieve constipation.




Before you take this medicine



Do not take:



  • If you are allergic to any of the ingredients


  • If you have severe stomach pain


  • For long periods of time, unless your doctor tells you to



Talk to your pharmacist or doctor:


  • If you have kidney problems

  • If you are elderly

  • If you take other medicines – cimetidine (for ulcers), diflunisal, indomethacin, aspirin or salicylates (for pain, swelling and rheumatism), digoxin (for heart problems), tetracycline antibiotics, iron, other medicines for indigestion

  • If you are pregnant

    You can take this medicine if you are breastfeeding.




How to take this medicine


Check the cap seal is not broken before first use. If it is, do not take the medicine. Shake the bottle well.



For indigestion:


  • Adults and children of 12 years and over
    • One to two 5 ml spoonfuls

    • Mix in a little water and take after meals, or when you need to




  • Children of 6 to 11 years
    • Half to one 5 ml spoonfuls depending on age

    • Mix in a little water and take after meals, or when you need to




  • Elderly
    • Take only if your doctor tells you to. Follow your doctor’s instructions.




For constipation:


  • Adults and children of 12 years and over
    • Five to ten 5 ml spoonfuls

    • Mix with a little warm water and take at bedtime




  • Children of 6 to 11 years
    • One to three 5 ml spoonfuls, depending on age

    • Mix with a little warm water and take at bedtime




  • Elderly, and children up to 6 years should only take this medicine if your doctor tells you to. Follow your doctor’s instructions.

Do not give to children under 6 years, unless your doctor tells you to.


Do not take regularly, or for long periods of time, (more than a week) unless your doctor tells you to.


If symptoms do not go away talk to your doctor.




If you take too much:


You may get watery diarrhoea or stomach pain. Talk to a doctor straight away if this happens.





Possible side effects


Most people will not have problems, but some may get some of these:


  • Diarrhoea
    If any side effect becomes severe, or you notice any side effect not listed here, please tell your pharmacist or doctor.

Do not freeze.



Keep all medicines out of the sight and reach of children.



Use by the date on the label edge.




Active ingredients


Each 5 ml of emulsion contains Magnesium Oxide 5.98% w/v, Magnesium Sulphate 0.075% w/v.


Also contains: purified water, chloroform.


PL 00014/5304


Text prepared 11/07




Manufactured by the Marketing Authorisation holder



The Boots Company PLC

Nottingham

NG2 3AA



If you need more advice ask your pharmacist.


BTC 17709 vF 25/01/08